SML1924

T1AM

≥98% (HPLC)

• Synonym(s): 3-Iodothyronamine hydrochloride, 4-[4-(2-Aminoethyl)-2-?iodophenoxy]phenol hydrochloride (1:1)
• Empirical Formula (Hill Notation): C₁₄H₁₄INO₂ · HCl
• CAS Number: 788824-64-6
• Molecular Weight: 391.63
• MDL number: MFCD11973725
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl
• InChI: 1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H
• InChI key: RVKVVMXTPQCCIX-UHFFFAOYSA-N

Description

Biochem/physiol Actions

3-iodothyronamine (T1AM) is present in vertebrate tissues and the circulatory system. Its physiological effects are the opposite of the thyroid hormone. T1AM acts as a neuromodulator as well as a hormone-like molecule.

T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone.

T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. T1AM is a potent agonist of trace amine-associated receptor TAAR1 (TAR1, TA1), a GPCR primarily found in the brain.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335,H410
• Precautionary Statements: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3