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S1946

Sigma-Aldrich

Anti-Sodium Channel NaV1.5 human antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-SCN5A, Anti-SKM2

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About This Item

MDL number:
MFCD04975341
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

western blot: 1:200 using human-Nav1.5 transfected HEK-293 cells

UniProt accession no.

Q14524

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SCN5A(6331)

Immunogen

GST fusion protein with residues 1978-2016 of human NaV1.5

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, and 0.05 % sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hugues Abriel et al.
Trends in cardiovascular medicine, 15(1), 35-40 (2005-03-30)
Na(v)1.5, the major cardiac voltage-gated Na(+) channel, plays a central role in the generation of the cardiac action potential and in the propagation of electrical impulses in the heart. Its importance for normal heart function has been recently exemplified by
Ling Wu et al.
Neuroreport, 13(18), 2547-2551 (2002-12-25)
Na(v)1.5 or SCN5A is a member of the voltage-dependent family of sodium channels. The distribution of Na(v)1.5 protein was investigated in the mouse brain using immunohistochemistry. Immunostaining with a Na(v)1.5-specific antibody revealed that Na(v)1.5 protein was localized in certain distinct

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