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P7876

Sigma-Aldrich

DL-Norephedrine hydrochloride

≥99%

Synonym(s):

(±)-Phenylpropanolamine hydrochloride, erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-Phenylpropanolamine hydrochloride

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About This Item

Linear Formula:
C6H5CH(OH)CH(NH2)CH3 · HCl
CAS Number:
154-41-6
Molecular Weight:
187.67
Beilstein:
3914299
EC Number:
205-826-7
MDL number:
MFCD00013019
UNSPSC Code:
12352116
PubChem Substance ID:
24898881
NACRES:
NA.25

Assay

≥99%

form

powder

mp

194-196 °C (lit.)

SMILES string

Cl.C[C@@H](N)[C@@H](O)c1ccccc1

InChI

1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9-;/m1./s1

InChI key

DYWNLSQWJMTVGJ-PRCZDLBKSA-N

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Biochem/physiol Actions

Mixed-acting sympathomimetic amine.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J Sullivan et al.
European urology, 36 Suppl 1, 89-95 (1999-07-07)
Many patients with incontinence do not need surgery - for these patients symptoms can often be considerably improved by conservative measures, including drugs. Several different pharmacological actions are potentially useful depending on the underlying cause of the incontinence: a) Detrusor
R J Fallis et al.
Neurology, 35(3), 405-407 (1985-03-01)
A 20-year-old woman using an oral diet aid preparation containing phenylpropanolamine presented with an intracerebral hemorrhage and angiographic evidence of cerebral vasculitis. Gas chromatography demonstrated phenylpropanolamine in the urine. Even when used within recommended guidelines, phenylpropanolamine usage should be included
Tung Si Ho et al.
Journal of chromatographic science, 44(6), 308-316 (2006-08-04)
Different organic borates, phosphates, sulphates, and carboxylic acids are evaluated as extraction carriers in three-phase liquid-phase microextraction (LPME). Hydrophilic basic drugs form ion-pairs with the carriers and are extracted as ion-pair complexes into an organic liquid membrane of n-octanol or
Abraham G Sarraf et al.
International journal of pharmaceutics, 481(1-2), 9-17 (2014-12-30)
The objective of this study was to tailor a drug release profile through the adjustment of some key processing parameters involved in melt-extrusion: die temperature, shear rate, die length and drug particle size. Two experimental designs were selected, namely a
R Dowse et al.
Journal of pharmaceutical sciences, 72(9), 1018-1020 (1983-09-01)
A high-performance liquid chromatographic analysis of phenylpropanolamine in human serum and urine without prior derivatization is presented. Using direct UV detection the method is sufficiently sensitive to detect 25 ng of drug/ml of serum or urine; the coefficients of variation
View All Related Papers

Chromatograms

application for HPLC

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