M006

Proglumide sodium salt

solid

• Synonym(s): 4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid sodium-potassium salt, N-Benzoyl-N′,N′-dipropyl-DL-isoglutamine sodium-potassium salt
• Empirical Formula (Hill Notation): C₁₈H₂₅N₂NaO₄
• CAS Number: 99247-33-3
• Molecular Weight: 356.39
• MDL number: MFCD00069301
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896533
• NACRES: NA.77

Properties

• form: solid
• color: white
• solubility: H₂O: soluble
• SMILES string: [Na+].CCCN(CCC)C(=O)C(CCC([O-])=O)NC(=O)c1ccccc1
• InChI: 1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1
• InChI key: UFMWGCINVOIJSO-UHFFFAOYSA-M
• Gene Information: human ... CCK(885) , CCKAR(886) , CCKBR(887) ; mouse ... CCK(12424) ; rat ... CCK(25298)

Description

Application

Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.

Biochem/physiol Actions

Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.

CCK antagonist; selectively blocks CNS effects.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves