Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

H9149

Sigma-Aldrich

α-Hydroxyalprazolam

powder, ≥98% (TLC)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H13ClN4O
CAS Number:
37115-43-8
Molecular Weight:
324.76
MDL number:
MFCD00171226
UNSPSC Code:
12352200
PubChem Substance ID:
24895845
NACRES:
NA.77

Quality Level

200

Assay

≥98% (TLC)

form

powder

drug control

Home Office Schedule 4.1; regulated under CDSA - not available from Sigma-Aldrich Canada

color

white to off-white

solubility

methylene chloride: ~20 mg/mL, clear, colorless to faintly yellow

SMILES string

OCc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4-n12

InChI

1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2

InChI key

ZURUZYHEEMDQBU-UHFFFAOYSA-N

Caution

store dessicated and protected from light

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R B Smith et al.
Psychopharmacology, 93(1), 105-112 (1987-01-01)
The relationships between alprazolam and metabolite concentrations and CNS effects were determined in a double-blind placebo controlled four-way crossover trial in 16 normal male volunteers. Active drug treatments consisted of 4-day regimens of 4 mg alprazolam PO daily as 2
Einosuke Tanaka et al.
Journal of forensic and legal medicine, 14(6), 348-351 (2007-07-17)
Alprazolam is widely used as a short-acting antidepressant and anxiolytic agent and its effect appears at very low doses while ethanol is used as a social drug worldwide. Sometimes, toxic interactions occur following combined administration of these two drugs. In
Hadi Molanaei et al.
European journal of clinical pharmacology, 68(5), 571-577 (2011-12-14)
To investigate the impact of persistent inflammation in hemodialysis (HD) patients on the pharmacokinetics of alprazolam, a cytochrome P450 (CYP) 3A4 substrate, and its metabolites and the role of HD in the impact of persistent inflammation in this clinical context.
Casey Jl Johnson et al.
Bioanalysis, 3(20), 2303-2310 (2011-10-21)
Conventional liquid-handling devices were employed, along with an improved punching device, to semi-automate dried blood spot (DBS) extraction of alprazolam, α-hydroxyalprazolam and midazolam from human whole blood. Liquid-handling devices were used to add internal standard to the DBS cards and
A D Fraser et al.
Journal of analytical toxicology, 17(7), 427-431 (1993-11-01)
Adinazolam is a triazolobenzodiazepine, currently under clinical investigation, that possesses antidepressant and anxiolytic activity. It has a short half-life (less than 3 h), and less than 2% of an oral dose is excreted unchanged. The major urinary metabolite is N-desmethyladinazolam
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service