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Key Documents

G7021

Sigma-Aldrich

D-(+)-Glucose

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99.5%

Synonym(s):

Dextrose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

Quality Level

Assay

≥99.5%

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

solubility

H2O: 2g + 15 mL (Tested)

application(s)

agriculture

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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General description

Glucose is the energy source of brain and of cells containing few or no mitochondria. It is also a substrate for anaerobic glycolysis. The human body stores glucose in the form of glycogen. Under low glucose conditions, it is released from liver and kidney via glycogen. Glucose is also required for the formation of di-, oligo- and polysaccharides.

Application

  • D-(+)-Glucose has been used for culturing of mammalian cells.
  • It has been used to study interactions between glucose and alanine and their influence on pentose phosphate pathway activity.
  • It has been used to perform glucose tolerance test in mice.

Other Notes

Mixed anomers

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Modulation of glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and malic enzyme activity by glucose and alanine in Atlantic salmon, Salmo salar L. hepatocytes.
Sanden M et al.
Aquaculture (Amsterdam, Netherlands), 221, 469-480 (2003)
Ferrier DR
Biochemistry (Lippincott's illustrated reviews) (2013)
A novel long term short interval physical activity regime improves body composition in mice.
Goh J and Ladiges WC
BMC Research Notes, 6, 66-66 (2013)
Ontogeny of circadian organization in the rat.
Yamazaki S et al.
Journal of biological rhythms, 24, 55-55 (2009)
Jashanpreet Kaur et al.
PloS one, 10(3), e0122354-e0122354 (2015-03-27)
Genotyping studies of Australian Scedosporium isolates have revealed the strong prevalence of a recently described species: Scedosporium aurantiacum. In addition to occurring in the environment, this fungus is also known to colonise the respiratory tracts of cystic fibrosis (CF) patients.

Protocols

Yeast Drop Out Bulletin. The selection of plasmids in yeast is based on the use of auxotrophic mutant strains, which cannot grow without a specific medium component (an amino acid, purine or pyrimidine). Transformation with a plasmid containing the mutated gene enables the transformant to grow on a medium lacking the required component. Although yeast can grow on a synthetic medium without any amino acids, better yield and growth rate can be achieved on richer media.

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