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D1925

Sigma-Aldrich

Demecolcine solution

10 μg/mL in HBSS, ACF Qualified, BioXtra

Synonym(s):

Colcemid™ solution, N-Deacetyl-N-methylcolchicine solution

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About This Item

CAS Number:
477-30-5
MDL number:
MFCD00075459
UNSPSC Code:
12352207
PubChem Substance ID:
24893569
NACRES:
NA.75

sterility

sterile-filtered

product line

BioXtra

form

liquid

concentration

10 μg/mL in HBSS

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2C3=CC=C(OC)C(=O)C=C13

InChI

1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1

InChI key

NNJPGOLRFBJNIW-HNNXBMFYSA-N

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Application

Used for cell synchronization by arresting them at metaphase. Qualified for use in animal component free applications.

Legal Information

Colcemid is a trademark of Ciba-Geigy Corporation

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Identification of the existence of G-quadruplex (G4) structure, from a specific G-rich sequence in cells, is critical to the studies of structural biology and drug development. Accumulating evidence supports the existence of G4 structure in vivo. Particularly, time-gated fluorescence lifetime
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Malignant mesothelioma is an aggressive tumour of serosal surfaces most commonly pleura. Characterised cell lines represent a valuable tool to study the biology of mesothelioma. The aim of this study was to develop and biologically characterise six malignant mesothelioma cell
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