B2557
8-Bromo-2′-monobutyryladenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer
>97% (HPLC), solid
Synonym(s):
Rp-8-Br-MB-cAMPS
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About This Item
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Quality Level
Assay
>97% (HPLC)
form
solid
packaging
vial of 5 μmol (2.5 mg solid)
solubility
water: soluble
storage temp.
−20°C
SMILES string
CCCC(=O)O[C@@H]1[C@@H]2O[P@](O)(=S)OC[C@H]2O[C@H]1n3c(Br)nc4c(N)ncnc34
InChI
1S/C14H17BrN5O6PS/c1-2-3-7(21)25-10-9-6(4-23-27(22,28)26-9)24-13(10)20-12-8(19-14(20)15)11(16)17-5-18-12/h5-6,9-10,13H,2-4H2,1H3,(H,22,28)(H2,16,17,18)/t6-,9-,10-,13-,27-/m1/s1
InChI key
KWTXVSKODFLFLA-WJCFKVOZSA-N
Application
Lipophilic precursor that is more lipophilic and membrane-permeable compared to Rp-8-Br-cAMPS.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Circulation research, 82(5), 557-565 (1998-04-07)
Cyclic nucleotides are known to modify voltage-gated (L-type) Ca2+ channel activity in vascular smooth muscle cells, but the exact mechanism(s) underlying these effects is not well defined. The purpose of the present study was to investigate the modulatory role of
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