Skip to Content
Merck
All Photos(1)

Documents

75447

Sigma-Aldrich

2-Oxoadipic acid

≥95.0% (HPLC)

Synonym(s):

α-Ketoadipic acid, 2-Oxoadipate, 2-Oxohexanedioic acid

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C6H8O5
CAS Number:
Molecular Weight:
160.12
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25

Assay

≥95.0% (HPLC)
≥97.0% (T)

form

powder

lipid type

saturated FAs

storage temp.

2-8°C

SMILES string

OC(=O)CCCC(=O)C(O)=O

InChI

1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)

InChI key

FGSBNBBHOZHUBO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application


  • Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate: Showcases the application of 2-oxoadipic acid in enzyme engineering, enhancing biocatalytic processes for the production of novel compounds, vital for pharmaceutical and chemical industries (Tariq et al., 2022).

Biochem/physiol Actions

Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metabolite transporters.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Natalia S Nemeria et al.
Biochimica et biophysica acta. Bioenergetics, 1859(9), 932-939 (2018-05-13)
Herein are reported findings in vitro suggesting both functional and regulatory cross-talk between the human 2-oxoglutarate dehydrogenase complex (hOGDHc), a key regulatory enzyme within the tricarboxylic acid cycle (TCA cycle), and a novel 2-oxoadipate dehydrogenase complex (hOADHc) from the final
D G Hine et al.
Biomedical mass spectrometry, 11(7), 332-339 (1984-07-01)
Numerous abnormal metabolites were identified in large amounts in the urine of hypoglycin-treated rats using capillary gas chromatography/mass spectrometry-computer analysis. These metabolites are not detectable in significant amounts in normal rats' urine. Ten of them have not been previously associated
A fatal case of 2-keto-, 2-hydroxy- and 2-aminoadipic aciduria: relation of organic aciduria to phenotype?
C Jakobs et al.
Journal of inherited metabolic disease, 15(2), 279-280 (1992-01-01)
Nikolaus Sonnenschein et al.
BMC systems biology, 6, 41-41 (2012-05-16)
Integrating gene expression profiles and metabolic pathways under different experimental conditions is essential for understanding the coherence of these two layers of cellular organization. The network character of metabolic systems can be instrumental in developing concepts of agreement between expression
D Darmaun et al.
Journal of chromatography, 620(1), 33-38 (1993-10-22)
A method is described for measuring glutamine (GLN) and alpha-ketoglutarate (KG) concentration and specific activity (SA) using high-performance liquid chromatography (HPLC). Plasma GLN and KG are separated on miniature ion-exchange columns. KG is derivatized with O-phenylene diamine, the derivative is

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service