17944

1α,25-Dihydroxyvitamin D₂

≥97.0% (sum of vitamin and previtamin, HPLC)

• Synonym(s): 1α,25-Dihydroxycalciferol
• Empirical Formula (Hill Notation): C₂₈H₄₄O₃
• CAS Number: 60133-18-8
• Molecular Weight: 428.65
• Beilstein: 5635017
• MDL number: MFCD00869499
• UNSPSC Code: 12352205
• PubChem Substance ID: 57647692
• NACRES: NA.79

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥97.0% (sum of vitamin and previtamin, HPLC)
• form: crystals
• color: white to light yellow
• storage temp.: −70°C
• SMILES string: C[C@H](\C=C\[C@H](C)C(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
• InChI: 1S/C28H44O3/c1-18(9-10-19(2)27(4,5)31)24-13-14-25-21(8-7-15-28(24,25)6)11-12-22-16-23(29)17-26(30)20(22)3/h9-12,18-19,23-26,29-31H,3,7-8,13-17H2,1-2,4-6H3/b10-9+,21-11+,22-12-/t18-,19+,23-,24-,25+,26+,28-/m1/s1
• InChI key: ZGLHBRQAEXKACO-XJRQOBMKSA-N

Description

Biochem/physiol Actions

Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301 + H311,H330,H372
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves