228680

Sodium diethyldithiocarbamate trihydrate

ACS reagent

• Synonym(s): Cupral, Diethyldithiocarbamic acid sodium salt
• Linear Formula: (C₂H₅)₂NCSSNa · 3H₂O
• CAS Number: 20624-25-3
• Molecular Weight: 225.31
• Beilstein: 3920507
• EC Number: 205-710-6
• MDL number: MFCD00150617
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853702
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• vapor density: 5.9 (vs air)
• composition: Na (as Na₂SO₄), 30.5-32.5%
• mp: 95-98.5 °C (lit.)
• SMILES string: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• InChI key: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Description

General description

Sodium diethyldithiocarbamate trihydrate may be used:

• To synthesize cis-dichlorobis(N,N-diethyldithiocarbamato) tin(IV) by reacting with tin(II) chloride.
• As an alternative to xanthates to generate carbamoyl radical precursors.
• To synthesize a soluble precursor polymer for poly(thienylene vinylene).
• To synthesize dichlorotetrakis(dimethyl sulfoxide)ruthenium (II), which can be a precursor to prepare other ruthenium complexes.[17}

Application

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues.

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves