AB2218

Anti-Aquaporin-4 Antibody

CHEMICON^®, rabbit polyclonal

• Synonym(s): AQP4, WCH4, MIWC
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• product name: Anti-Aquaporin 4 Antibody, Chemicon^®, from rabbit
• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, mouse, rat
• manufacturer/tradename: Chemicon^®
• technique(s): western blot: suitable
• NCBI accession no.: NM_001650.4; NM_004028.3
• UniProt accession no.: P55087
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... AQP4(361)

Description

General description

The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes.

Specificity

Recognizes Aquaporin 4.

The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).

Immunogen

Epitope: C-Terminus

Synthetic Linear Peptide

Application

Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.

Optimal working dilutions must be determined by end user.

Target description

~34 kDa

Linkage

Replaces: AB3068

Physical form

ImmunoAffinity Purified

Purified in PBS with 0.05% NaN₃

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Analysis Note

Control
Tested on adult rat brain lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable