8.43942

Propanephosphonic acid anhydride

(50% solution in ethyl acetate) for synthesis T3P

• Synonym(s): 2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, Propylphosphonic anhydride, T3P
• UNSPSC Code: 12352108
• NACRES: NA.22

Properties

• vapor pressure: 97 hPa ( 20 °C)
• Quality Level: 200
• form: liquid
• bp: 77 °C/1013 hPa (ethyl acetate)
• transition temp: flash point -4 °C (ethyl acetate)
• density: 1.08 g/cm³ at 20 °C
• storage temp.: 2-8°C

Description

Application

• Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids: The study reports the synthesis of naturally occurring cyclotetrapeptides using 1-propanephosphonic acid anhydride, noting unexpected findings in cyclization patterns. (Zhang et al., 2017).

Analysis Note

Assay (T3P) (NMR): ≥ 40.0 %
Pyropropanephosphonic acid (NMR): ≤ 10.0 %
Propanephosphonic acid (NMR): ≤ 0.50 %
Ethyl acetate (calculated): ≤ 50.0 %

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H290 - H314 - H317 - H336
• Precautionary Statements: P210 - P233 - P234 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 24.8 °F - ethyl acetate
• Flash Point(C): -4 °C - ethyl acetate