1.07164

Paraffin pastilles

solidification point about 56-58°C for histology

• Synonym(s): Paraffin pastilles, Paraffin pastilles solidification point, Paraffin for Histology
• CAS Number: 64742-51-4
• UNSPSC Code: 41116124
• EC Index Number: 265-154-5

Properties

• Quality Level: 400
• form: solid
• potency: >5000 mg/kg LD₅₀, oral (Rat); >3000 mg/kg LD₅₀, skin (Rabbit)
• color: white
• kinematic viscosity: 4.2 cSt(100 °C)
• transition temp: flash point >100 °C
• density: 0.9 g/cm³ at 20 °C
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 15-25°C

Description

General description

Paraffin pastilles - solidification point about 56-58 °C for histology, are a highly pure ready-to-use paraffin product. Paraffins are the materials generally used to embed the specimens for histological applications. In order to achieve uniformous ribbon-sectioning quality, defined hardness and homogeneity of the processed material is necessary. This can be guarranteed through high-quality raw materials and defined melting points. The melting point of Paraffin is 56-58°C. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU).

Application

• Clinical application of targeted tumour sequencing tests for detecting ERBB2 amplification and optimizing anti-HER2 therapy in gastric cancer.: This study demonstrates the use of paraffin-embedded tissue samples in targeted tumor sequencing to identify patients suitable for anti-HER2 therapy, highlighting paraffin′s utility in preserving sample integrity for genetic analysis (Ichikawa et al., 2024).


• Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker.: Describes a novel proteomics method using formalin-fixed paraffin-embedded (FFPE) samples to identify biomarkers for hormone-induced changes in cellular structures, advancing tissue-specific molecular diagnostics (Faktor et al., 2024).


• TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.: Introduces TSWIFT, a new technique for the iterative staining of paraffin-embedded human brain sections, providing enhanced imaging capabilities for neurological research (Porter et al., 2024).


• [Optimal melanin removal methods for HE staining, immunohistochemistry and molecular detection].: Investigates various methods for melanin removal in HE staining processes involving paraffin-embedded samples, crucial for accurate histopathological and immunohistochemical analyses (Zhang et al., 2024).


• Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw.: This case report utilizes paraffin-embedded sections to uncover novel histopathological insights into osteonecrosis, demonstrating paraffin′s role in detailed structural analysis in pathological conditions (Koizumi et al., 2024).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable