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Key Documents

840465P

Avanti

18:0 PG

Avanti Research - A Croda Brand

Synonym(s):

1,2-dioctadecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DSPG; PG(18:0/18:0); 110649

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About This Item

Empirical Formula (Hill Notation):
C42H82O10PNa
CAS Number:
Molecular Weight:
801.06
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-distearoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (840465P-1g)
pkg of 1 × 200 mg (840465P-200mg)
pkg of 1 × 25 mg (840465P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

storage temp.

−20°C

InChI

1S/C42H83O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h39-40,43-44H,3-38H2,1-2H3,(H,47,48);/q;+1/p-1/t39?,40-;/m1./s1

InChI key

YNQYZBDRJZVSJE-QTOMIGAPSA-M

Packaging

20 mL Clear Glass Screw Cap Vial (840465P-1g)
5 mL Amber Glass Screw Cap Vial (840465P-200mg)
5 mL Amber Glass Screw Cap Vial (840465P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Naomi Benne et al.
Journal of controlled release : official journal of the Controlled Release Society, 318, 246-255 (2019-12-10)
Regulatory T cells (Tregs) are vital for maintaining a balanced immune response and their dysfunction is often associated with auto-immune disorders. We have previously shown that antigen-loaded anionic liposomes composed of phosphatidylcholine (PC) and phosphatidylglycerol (PG) and cholesterol can induce
Margaret W Ndinguri et al.
Journal of drug delivery, 2012, 592602-592602 (2012-12-06)
Cancer treatment by chemotherapy is typically accompanied by deleterious side effects, attributed to the toxic action of chemotherapeutics on proliferating cells from nontumor tissues. The cell surface proteoglycan CD44 has been recognized as a cancer stem cell marker. The present
Noel Vera-González et al.
Journal of biomedical materials research. Part A, 108(11), 2263-2276 (2020-05-05)
Fungal infections can cause significant patient morbidity and mortality. Nanoparticle therapeutics have the potential to improve treatment of these infections. Here we report the development of liposomal nanoparticles incorporating anidulafungin, a potent antifungal, with the goal of increasing its solubility
Parvin Zamani et al.
Life sciences, 252, 117646-117646 (2020-04-10)
Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells causing resistance to immunotherapies in cancer tumors. In the current study, various immunogenic and therapeutic features of the combination therapies with non-liposomal Doxorubicin (Dox) and the E75 immunogenic peptide (Pep), derived from the
Kevin A Carter et al.
Nature communications, 5, 3546-3546 (2014-04-05)
The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential to selectively enhance localized delivery. Here we describe liposomes doped with porphyrin-phospholipid that are permeabilized directly by near-infrared

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