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Key Documents

810281C

Avanti

TopFluor® PC

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C48H83BF2N3O8P
CAS Number:
1246355-63-4
Molecular Weight:
909.97
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810281C-1mg)
pkg of 5 × 1 mL (810281C-5mg)
pkg of 5 × 2 mL (810281C-10mg)

manufacturer/tradename

Avanti Polar Lipids 810281C

concentration

1 mg/mL (810281C-10mg)
1 mg/mL (810281C-1mg)
1 mg/mL (810281C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholines (PC) are the building blocks of eukaryotic membranes. PC is an important component of the mucosal layer of the colon and is a strong bilayer-forming lipid.

Application

TopFluor® PC has been used as a component in the for fluorescent studies using small unilamellar vesicles. It has also been used in the preparation of unilamellar phospholipid liposomes.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism.

Packaging

5 mL Amber Glass Screw Cap Vial (810281C-10mg)
5 mL Amber Glass Screw Cap Vial (810281C-1mg)
5 mL Amber Glass Screw Cap Vial (810281C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The
Integrative Medicine - E-Book (2017)
Mammalian nonmuscle myosin II binds to anionic phospholipids with concomitant dissociation of the regulatory light chain
Liu X, et al.
The Journal of Biological Chemistry, 291(48), 24828-24837 (2016)
The
The Membranes of Cells (2016)
Optimizing a ultrahigh pressure liquid chromatography-time of flight-mass spectrometry approach using a novel sub-2 mum core-shell particle for in depth lipidomic profiling of Caenorhabditis elegans
Witting M, et al.
Journal of Chromatography A, 1359, 91-99 (2014)
Formation of supported lipid bilayers containing phase-segregated domains and their interaction with gold nanoparticles
Melby ES, et al.
Environmental science. Nano, 3(1), 45-55 (2016)
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