791645C

18:1-d7-cholesterol

Avanti Research^™ - A Croda Brand 791645C

• Synonym(s): cholest-5-en-3β-yl oleate-d7
• Empirical Formula (Hill Notation): C₄₅H₇₁ D₇O₂
• CAS Number: 2260669-48-3
• Molecular Weight: 658.14
• UNSPSC Code: 41141804
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (791645C-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 791645C
• concentration: 1 mg/mL (791645C-1mg)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Cholesteryl oleate is a cholesteryl ester. 18:1-d7-cholesterol is a deuterated oleic acid cholesteryl ester.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

18:1-d7-cholesterol may be used in the reconstitution of acetylated low-density lipoprotein (acLDL) liposome for trafficking studies in U2OS-SRA cells.

Biochem/physiol Actions

Elevation in cholesterol ester levels and its accumulation is implicated in prostate cancer (PCa). Cholesteryl oleate, may serve as a potential biomarker for diagnosis of PCa.

Packaging

5 mL Clear Glass Sealed Ampule (791645C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• WGK: WGK 3