936375

DBCO Acid

≥95%

• Synonym(s): 11,12-Didehydro-γ-oxodibenz[b,f]azocine-5(6H)-butanoic acid (ACI), Dibenz[b,f]azocine-5(6H)-butanoic acid, 11,12-didehydro-γ-oxo- (ACI)
• Empirical Formula (Hill Notation): C₁₉H₁₅NO₃
• CAS Number: 1353016-70-2
• Molecular Weight: 305.33
• MDL number: MFCD28064336
• UNSPSC Code: 12352106
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95%
• form: powder or crystals
• color: white to off-white
• mp: 163-164 °C
• storage temp.: −20°C
• SMILES string: OC(CCC(N1CC2=CC=CC=C2C#CC3=CC=CC=C13)=O)=O
• InChI: InChI=1S/C19H15NO3/c21-18(11-12-19(22)23)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13H2,(H,22,23)

Description

Application

DBCO Acid is a bifunctional building block comprising of an acid terminus useful for reaction with amine containing linkers in presence of activators such as EDC or HATU and a dibenzocyclooctyne (DBCO) terminus useful for copper-free click chemistry.

Features and Benefits

DBCO compounds react with azides without need of Cu(I) catalyst due to the strained nature of alkyne resulting in formation of fast and stable triazole linkage.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable