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Key Documents

901798

Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, biotin functionalized, PEG 3000 coated, 1 mg/mL in deionized water

Synonym(s):

Fluorescent nanoparticles, Nanodiamonds

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About This Item

UNSPSC Code:
12352100
NACRES:
NA.23

form

nanoparticles

composition

Nitrogen vacancy, ~3 ppm NV centers

concentration

1 mg/mL in deionized water

avg. part. size

140 nm

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General description

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, biotin functionalized, PEG 3000 coated, 1 mg/mL in deionized water), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxicity and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centers exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. Our biotin functionalized NDs are ideal for attachment with streptavidin modified targets.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond.
Krueger A, et al.
Advances in Functional Materials, 22, 890-890 (2012)
The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent
Vaijayanthimala V, et al.
Biomaterials, 33(31), 7794-7802 (2012)
Nanodiamond bioconjugate probes and their collection by electrophoresis.
Hens SC, et al.
Diamond and Related Materials, 17, 1858-1858 (2008)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting.
Chang B, et al.
Advances in Functional Materials, 23, 5737-5737 (2013)
Yuen Yung Hui et al.
Optics express, 18(6), 5896-5905 (2010-04-15)
Dynamics of fluorescent diamond nanoparticles in HeLa cells has been studied with two-photon fluorescence correlation spectroscopy (FCS). Fluorescent nanodiamond (FND) is an excellent fluorescent probe for bioimaging application, but they are often trapped in endosomes after cellular uptake. The entrapment
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