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Key Documents

528056

Sigma-Aldrich

Thioglycolic acid

≥99%

Synonym(s):

Mercaptoacetic acid

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About This Item

Linear Formula:
HSCH2COOH
CAS Number:
Molecular Weight:
92.12
Beilstein:
506166
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

3.2 (vs air)

Quality Level

vapor pressure

0.4 mmHg ( 25 °C)

Assay

≥99%

autoignition temp.

662 °F

availability

available only in EU

refractive index

n20/D 1.505 (lit.)

bp

96 °C/5 mmHg (lit.)

mp

−16 °C (lit.)

density

1.326 g/mL at 20 °C (lit.)

functional group

carboxylic acid
thiol

storage temp.

2-8°C

SMILES string

OC(=O)CS

InChI

1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)

InChI key

CWERGRDVMFNCDR-UHFFFAOYSA-N

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Application

Thioglycolic acid (TGA) can be used as:
  • A sulfur source and stabilizing agent to synthesize nanocrystalline metal sulfides via hydrothermal reaction. TGA also controls the morphology and particle sizes of nanocrystalline metal sulfides during the process.
  • An effective agglomeration suppressant for the agglomeration of sulfurized mineral pyrite.
  • A reactant to prepare 2,3-disubstituted-thiazolidin-4-one derivatives by one-pot cyclo-condensation reaction with various aldehydes and amines using supported protic acid catalyst.
  • A capping or stabilizing agent to synthesize CdTe quantum dots with controllable photoluminescence wavelengths.

Legal Information

Product of Arkema

Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

266.0 °F - closed cup

Flash Point(C)

130 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Effect of oxidation and thioglycolic acid on separation of coal and pyrite by selective oil agglomeration
DRZYMALA J and Wheelock TD
International Journal of Coal Preparation and Utilization, 14(1-2), 1-11 (1994)
Pyrite suppression in oil agglomeration of coal
Drzymala J, et al.
Proceedings, 1005-1008 (1991)
Baofu Han et al.
Colloids and surfaces. B, Biointerfaces, 100, 209-214 (2012-07-07)
Fluorescent carbon dots (CDs) were solvothermaly synthesized in water-glycol medium by using glucose as carbon source and then modified with polyethyleneimine (PEI) for the first time to improve fluorescence quality. The as-prepared CDs were monodispersed sphere particles with a diameter
Markus Aswendt et al.
Nanomedicine (London, England), 10(16), 2499-2512 (2015-08-22)
We validated novel bimodal iron oxide particles as substitute of ferumoxides for efficient labeling of human neural stem cells (NSCs). The dextrane-coated FeraTrack Direct (FTD)-Vio particles have additional far-red fluorophores for microscopic cell analysis. MR relaxometry, spectrophotometric iron determination and
Zhengqing Liu et al.
Analytica chimica acta, 745, 78-84 (2012-09-04)
A novel fluorescent probe for Cu(2+) determination based on the fluorescence quenching of glyphosate (Glyp)-functionalized quantum dots (QDs) was firstly reported. Glyp had been used to modify the surface of QDs to form Glyp-functionalized QDs following the capping of thioglycolic

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