123889

α,α′-Dichloro-o-xylene

98%

• Synonym(s): 1,2-Bis(chloromethyl)benzene, o-Xylylene dichloride
• Linear Formula: C₆H₄(CH₂Cl)₂
• CAS Number: 612-12-4
• Molecular Weight: 175.06
• Beilstein: 2043675
• EC Number: 210-291-8
• MDL number: MFCD00000903
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847586
• NACRES: NA.22

Properties

• Assay: 98%
• form: solid
• bp: 239-241 °C (lit.)
• mp: 51-55 °C (lit.)
• SMILES string: ClCc1ccccc1CCl
• InChI: 1S/C8H8Cl2/c9-5-7-3-1-2-4-8(7)6-10/h1-4H,5-6H2
• InChI key: FMGGHNGKHRCJLL-UHFFFAOYSA-N

Description

General description

α,α′-Dichloro-o-xylene reacts with elemental tellurium and NaI in 2-methoxyethanol to form 1,1-diiodo-3,4-benzo-1-telluracyclopentane.

Application

α,α′−Dichloro-o-xylene was used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335,H410
• Precautionary Statements: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 257.0 °F - closed cup
• Flash Point(C): 125 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves