GSR
glutathione reductase
Synonyms:
Species:
Human GSR (2936), Mouse Gsr (14782), Rat Gsr (116686), sheep GSR (101114416), domestic guinea pig Gsr (100718789), naked mole-rat Gsr (101696661), Zebrafish gsr (553575), chicken GSR (771783), cow GSR (506406), domestic cat GSR (101094413)
UniProtKB ID:
Gene ID:
- Human(2936) Summary: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
- Mouse(14782) glutathione reductase
- Rat(116686) glutathione reductase
- sheep(101114416) glutathione reductase
- domestic guinea pig(100718789) glutathione reductase
- naked mole-rat(101696661) glutathione reductase
- Zebrafish(553575) glutathione reductase
- chicken(771783) glutathione reductase
- cow(506406) glutathione reductase
- domestic cat(101094413) glutathione reductase
- dog(475596) glutathione reductase
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