DHFR
dihydrofolate reductase
Synonyms:
DHFRP1, DYR
Species:
Human DHFR (1719), Mouse Dhfr (13361), Rat Dhfr (24312), Zebrafish dhfr (81882), cow DHFR (508809), domestic cat DHFR (101087964), dog DHFR (609048), chicken DHFR (427317), fruit fly Dhfr (42003), sheep DHFR (101121421) ...More
UniProtKB ID:
Gene ID:
- Human(1719) Summary: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008]
- Mouse(13361) dihydrofolate reductase
- Rat(24312) dihydrofolate reductase
- Zebrafish(81882) dihydrofolate reductase
- cow(508809) dihydrofolate reductase
- domestic cat(101087964) dihydrofolate reductase
- dog(609048) dihydrofolate reductase
- chicken(427317) dihydrofolate reductase
- fruit fly(42003) Dihydrofolate reductase
- sheep(101121421) dihydrofolate reductase
- Domestic Rabbit(100359209) dihydrofolate reductase
- domestic guinea pig(100729225) dihydrofolate reductase
- naked mole-rat(101701790) dihydrofolate reductase
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Small Molecule - Inhibitor
Product Number
Description
Species
Methotrexate for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Methotrexate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human