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Merck

STAT4

signal transducer and activator of transcription 4

Synonyms:
SLEB11
Species:
UniProtKB ID:
Gene ID:
  • Human(6775) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
  • Mouse(20849) signal transducer and activator of transcription 4
  • Rat(367264) signal transducer and activator of transcription 4
  • Zebrafish(368519) signal transducer and activator of transcription 4
  • chicken(768406) signal transducer and activator of transcription 4
  • dog(478845) signal transducer and activator of transcription 4
  • domestic cat(101080650) signal transducer and activator of transcription 4
  • Horse(100054693) signal transducer and activator of transcription 4
  • domestic guinea pig(100726892) signal transducer and activator of transcription 4
  • Domestic Rabbit(100344146) signal transducer and activator of transcription 4
  • naked mole-rat(101718558) signal transducer and activator of transcription 4
  • cow(515988) signal transducer and activator of transcription 4
  • sheep(101117562) signal transducer and activator of transcription 4

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ELISA

Product Number
Description
Species
Phosphotyrosine STAT4 / Signal Transducer and Activator of Transcription 4 ELISA Kit, ,
Species
human
Cell-Based ELISA for detecting phospho-STAT4 (pTyr693) in cultured cell lines, 96 assays,
Species
mouse, human
Cell-Based ELISA for detecting phospho-STAT4 (pTyr693) in cultured cell lines, 192 assays,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-STAT4 Antibody, clone 10H10O9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-STAT4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-STAT4 (Ab-693) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-phospho-STAT4 (pTyr693) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-STAT4 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, pig, rabbit
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
STAT4 human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Stat4,
Species
mouse
MISSION® esiRNA, targeting human STAT4,
Species
human