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Merck

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Synonyms:
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT
Species:
Human SERPINA1 (5265), Rat Serpina1 (24648), Zebrafish serpina1 (322701), domestic cat SERPINA1 (101080897), dog SERPINA1 (480422), chicken SERPINA1 (423434), cow SERPINA1 (280699), sheep SERPINA1 (443388)
UniProtKB ID:
P01009, A6PX14, B2RDQ8, Q0PVP5, Q13672, Q53XB8, Q5U0M1, Q7M4R2
Gene ID:
  • Human(5265) Summary: The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(24648) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • Zebrafish(322701) serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • domestic cat(101080897) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • dog(480422) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • chicken(423434) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • cow(280699) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • sheep(443388) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

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ELISA

Product Number
Description
Species
RAB1079
Human Serpin A1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2109236
Anti-SERPINA1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
SAB5702993
Anti-Alpha-1 Antitrypsin (SERPINA1) Antibody, clone 1J3E7, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
HPA001292
Anti-SERPINA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB4200198
Anti-Alpha-1-Antitrypsin (AAT) antibody,Mouse monoclonal, clone 1C2, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot
HPA000927
Anti-SERPINA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP6260
SERPINA1/A1AT human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
A9024
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human
A6150
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
EHU017931
MISSION® esiRNA, targeting human CTD-2600O9.1,
Species
human
EHU090971
MISSION® esiRNA, targeting human SERPINA1,
Species
human