POLG
polymerase (DNA directed), gamma
Synonyms:
MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
Species:
Human POLG (5428), Mouse Polg (18975), Rat Polg (85472), naked mole-rat Polg (101700433), domestic guinea pig Polg (100728907), cow POLG (533090), sheep POLG (101123414), Zebrafish polg (100150924), dog POLG (488732), chicken POLG (404292) ...More
UniProtKB ID:
Gene ID:
- Human(5428) Summary: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18975) polymerase (DNA directed), gamma
- Rat(85472) polymerase (DNA directed), gamma
- naked mole-rat(101700433) polymerase (DNA directed), gamma
- domestic guinea pig(100728907) polymerase (DNA directed), gamma
- cow(533090) polymerase (DNA directed), gamma
- sheep(101123414) polymerase (DNA directed), gamma
- Zebrafish(100150924) polymerase (DNA directed), gamma
- dog(488732) polymerase (DNA directed), gamma
- chicken(404292) polymerase (DNA directed), gamma
- domestic cat(101083771) polymerase (DNA directed), gamma
- Horse(100053827) polymerase (DNA directed), gamma
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-DNA Polymerase gamma Antibody, clone 9V9D9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-DNA polymerase subunit gamma-1 Antibody/POLG, 1.0 mg/mL, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
immunoprecipitation (IP)