CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Synonyms:
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Species:
Human CDKN1B (1027), Mouse Cdkn1b (12576), Rat Cdkn1b (83571), chicken CDKN1B (374106), dog CDKN1B (403429), cow CDKN1B (512613), domestic cat CDKN1B (493958), chicken CDKN1B (769872), naked mole-rat Cdkn1b (101698721), domestic guinea pig Cdkn1b (100729359) ...More
UniProtKB ID:
Gene ID:
- Human(1027) Summary: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
- Mouse(12576) cyclin-dependent kinase inhibitor 1B
- Rat(83571) cyclin-dependent kinase inhibitor 1B
- chicken(374106) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- dog(403429) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- cow(512613) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- domestic cat(493958) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- chicken(769872) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- naked mole-rat(101698721) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- domestic guinea pig(100729359) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- sheep(100127219) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- Domestic Rabbit(100009037) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KIP1/CDKN1B, Internal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, cat, human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-p27 Kip1 (pThr198) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-p27Kip1antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM302, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-phospho-Kip1 (Thr187) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-CDKN1B, (C-terminal) antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
p27KIP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human