20018AST
Astec® CYCLOBOND™ I 2000 Chiral HPLC Column
5 μm particle size, L × I.D. 10 cm × 2.1 mm
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Recommended Products
material
stainless steel column
Quality Level
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-50 °C temperature
172 bar pressure (2500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
10 cm × 2.1 mm
matrix
silica particle platform
matrix active group
cyclodextrin, beta- phase
particle size
5 μm
pore size
100 Å
operating pH
3.5-7
separation technique
chiral
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General description
CYCLOBOND I 2000 is bonded with β-cyclodextrin by a patented process to produce a stable matrix with the cyclodextrin arranged in such a way as to retain its most valuable property of forming inclusion complexes. This allows them to effect numerous chemical separations by selectively including into their cavities a wide variety of organic molecules. Non-inclusion type separations are also possible with the polar organic mode for a wide variety of molecule types.
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
- Bonded phase: Underivatized, native β-cyclodextrin
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Liquid chromatographic resolution of enantiomers of deltahedral carborane and metallaborane derivatives
Plesek, Jaromir, et al.
Journal of Chromatography A, 626 (2), 197-206 (1992)
High-performance liquid chromatography of diastereomeric flavanone glycosides in Citrus on a ?-cyclodextrin-bonded stationary phase (Cyclobond I)
Krause, Martin; Galensa, Rudolf
Journal of Chromatography A, 588 (1-2), 41-45 (1991)
Chiral separations of ?-blocking drug substances using chiral stationary phases
Ekelund, Jens, et al.
Journal of Chromatography A, 708 (2), 253-261 (1995)
A F Casy et al.
Journal of pharmaceutical and biomedical analysis, 9(10-12), 787-792 (1991-01-01)
The interaction of beta-cyclodextrin with a series of structurally related chiral thromboxane antagonists was investigated using NMR and RP-HPLC. HPLC studies used both a cyclodextrin bonded phase (Cyclobond I), and beta-cyclodextrin as a mobile phase additive with an achiral C8
High-performance liquid chromatographic determination of ibuprofen, its metabolites and enantiomers in biological fluids
Geisslinger, G., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 491, 139-149 (1989)
Related Content
CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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