SML1785

Landiolol hydrochloride

≥98% (HPLC)

• Synonym(s): 4-[(2S)-2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-benzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester hydrochloride, 4-[2-Hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-benzenepropanoic acid [S-(R*,R*)]-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester hydrochloride, ONO 1101, ONO-1101
• Empirical Formula (Hill Notation): C₂₅H₃₉N₃O₈ · HCl
• CAS Number: 144481-98-1
• Molecular Weight: 546.05
• MDL number: MFCD01937430
• UNSPSC Code: 12352200
• PubChem Substance ID: 329826064
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 25 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1(C)OC[C@@H](COC(CCC2=CC=C(OC[C@@H](O)CNCCNC(N3CCOCC3)=O)C=C2)=O)O1.[H]Cl
• InChI: 1S/C25H39N3O8.ClH/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28;/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31);1H/t20-,22+;/m0./s1
• InChI key: DLPGJHSONYLBKP-IKGOIYPNSA-N

Description

Biochem/physiol Actions

Landiolol is an ultra-short acting cardioselective β-adrenoceptor antagonist the exhibit β1-selectivity.

Landiolol is an ultra-short acting cardioselective β-adrenoceptor antagonist the exhibit β1-selectivity. New data shows that landiolol lacks pharmacochaperoning activity.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable