SCP0123

[D-Gln⁴]-Desmopressin

• Empirical Formula (Hill Notation): C₄₆H₆₄N₁₄O₁₂S₂
• Molecular Weight: 1069.22
• UNSPSC Code: 12352209
• NACRES: NA.32

Properties

• Assay: ≥95% (HPLC)
• form: lyophilized
• composition: Peptide Content, ≥75%
• storage condition: protect from light
• storage temp.: −20°C

Description

Amino Acid Sequence

Mpa-Tyr-Phe-D-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2

Application

Desmopressin is a synthetic alternative to arginine vasopressin that acts via V2 receptors in renal collecting ducts to regulate water retention. [D-Gln4]-Desmopressin may be used in studies of conformations and receptor activity of desmopressin analogues.

Biochem/physiol Actions

Desmopressin is considered safe for consumption during first and second trimesters of pregnancy. But, it shows high risk of arterial thrombosis. It is known to induce platelet factor VIII and VWF (Von Willebrand factor) and improves platelet aggregation. Desmopressin is found helpful in congenital bleeding disorder.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable