SAB4503583

Anti-CD4 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 51 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P01730
• UniProt accession no.: P01730
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CD4(920)

Description

General description

Anti-CD4 Antibody detects endogenous levels of total CD4 protein.

CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31.

Immunogen

The antiserum was produced against synthesized peptide derived from human CD4.

Immunogen Range: 401-450

Application

Anti-CD4, C-Terminal antibody has been used in immunohistochemical staining.

Biochem/physiol Actions

CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serve as a primary receptor for HIV-1 entry.This molecule plays an important role on cell membrane mechanical characteristics and can be used in the development of cell biology and medicine.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable