RAB0657
Human FABP3 / Fatty Acid-binding Protein, Heart ELISA Kit
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 ng/mL
standard curve range: 2.05-200 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FABP3(2170)
General description
Fatty acid-binding protein-3 (FABP3) is a small cytoplasmic protein, which is a member of the multigene family of FA-binding proteins. It is widely expressed in the heart. This gene is mapped to human chromosome 1p35.
SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates. SRC is overexpressed and activated in a large number of human malignancies and has been linked to the development of cancer and progression to distant metastases. In addition to increasing cell proliferation, a key role of SRC in cancer seems to be the ability to promote invasion and motility, functions that might contribute to tumour progression
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Fatty acid-binding protein-3 (FABP3) participates in cardiac metabolism. It plays an important role in the intracellular uptake of fatty acids and their migration towards the mitochondrial β-oxidation system.
Other Notes
A sample Certificate of Analysis is available for this product.
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Claire J C Huguenard et al.
Frontiers in physiology, 11, 12-12 (2020-02-23)
The differential diagnosis between mild Traumatic Brain Injury (mTBI) sequelae and Post-Traumatic Stress Disorder (PTSD) is challenging due to their symptomatic overlap and co-morbidity. As such, there is a need to develop biomarkers which can help with differential diagnosis of
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Iranian journal of kidney diseases, 13(2), 120-128 (2019-04-17)
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BMJ open, 9(10), e031774-e031774 (2019-10-20)
The diagnosis of transient ischaemic attack (TIA) based on symptoms and signs can be challenging and would greatly benefit from a rapid serum biomarker of brain ischaemia. We aimed to quantify the added diagnostic value of serum biomarkers in patients
The circulating level of FABP3 is an indirect biomarker of microRNA-1
Varrone F, et al.
Journal of the American College of Cardiology, 61(1), 88-95 (2013)
Shanshan Wu et al.
European journal of medical research, 25(1), 2-2 (2020-03-18)
Acute coronary syndrome (ACS) is a serious type of cardiovascular diseases. This study aimed to investigate the expression patterns and clinical value of microRNA-145 (miR-145) in ACS patients, and further uncover the function of miR-145 in ACS rats. Quantitative real-time
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