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L5777

Sigma-Aldrich

N-Lauroylsarcosine sodium salt

BioXtra, ≥97% (TLC)

Synonym(s):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
Beilstein:
5322974
EC Number:
205-281-5
MDL number:
MFCD00042728
UNSPSC Code:
12161900
PubChem Substance ID:
57654332
NACRES:
NA.25

description

anionic

product line

BioXtra

Assay

≥97% (TLC)

form

powder

mol wt

micellar avg mol wt 600
average mol wt 600

aggregation number

2

impurities

≤0.1% Insoluble matter
≤0.1% Phosphorus (P)

CMC

14.6 mM (20-25°C)

solubility

H2O: 0.1 M, clear, colorless to very faintly yellow

cation traces

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.005%
K: ≤0.01%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.01%
Zn: ≤0.0005%

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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General description

N-Lauroylsarcosine sodium salt is an anionic surfactant.

Application

N-Lauroylsarcosine sodium salt has been used in a study to assess involvement of histamine released from epidermal keratinocytes. It has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.

Other Notes

Anionic surfactant.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H315,H318,H330

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

512.6 °F - closed cup

Flash Point(C)

267 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.
Gültekin Tamgüney et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(35), 15002-15006 (2009-08-27)
Prions are infectious proteins that cause fatal neurodegenerative diseases. Because astrocytic gliosis marked by the deposition of fibrils composed of GFAP is a prominent feature of prion disease, we asked whether GFAP might be used as a surrogate marker for
Linda A Terry et al.
Veterinary research, 42, 65-65 (2011-05-20)
Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence from animal models has implicated urine, blood, saliva, placenta and faeces as possible sources of the infection.
Sang Su Kwak et al.
Nature communications, 11(1), 1377-1377 (2020-03-15)
The relationship between amyloid-β (Aβ) species and tau pathology in Alzheimer's disease (AD) is not fully understood. Here, we provide direct evidence that Aβ42/40 ratio, not total Aβ level, plays a critical role in inducing neurofibrillary tangles (NTFs) in human
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