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Key Documents

H0146

Sigma-Aldrich

Horse serum

liquid

Synonym(s):

Serum

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

horse serum

Quality Level

sterility

non-sterile

form

liquid

contains

preservative

shipped in

dry ice

storage temp.

−20°C

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General description

Horse serum displays homogeneity between fetal bovine serum and fetal calf serum .It has low levels of polyamine oxidase.
Horse serum is pooled from a normal donor herd.

Application

Horse serum has been used as a supplement in minimum essential medium for cerebrocortical neuronal−glial cell cultures and RPMI-40 medium for PC12 cells derived from rat adrenal medulla pheochromocytoma. It has also been used in immunohistochemistry of Florida manatee brain sections.
Normal horse serum may be used as a blocking agent and controls in immunoassays. For immunohistochemistry and immunocytochemistry, 10% horse serum was used as blocking agent in various Studies.
Horse serum was used in immunostaining for blocking non-specific antibodies binding.

Biochem/physiol Actions

The horse serum is an alternative to bovine serum for growth factors and hormones for cell culture studies. Horse serum stimulates fibroblast differentiation and extracellular matrix (ECM) and cytokines synthesis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neuron types in the presumptive primary somatosensory cortex of the Florida manatee (Trichechus manatus latirostris)
Reyes LD, et al.
Brain, behavior and evolution, 86(3-4), 210-231 (2015)
Hepcidin mediates transcriptional changes in ferroportin mRNA in differentiated neuronal-like PC12 cells subjected to iron challenge
Helgudottir S, et al.
Molecular Neurobiology, 56(4), 2362-2374 (2019)
Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling
Hannan NJ et al
J. Clin. Endocr., 89, 6119-6129 (2004)
Sevoflurane protects rat mixed cerebrocortical neuronal-glial cell cultures against transient oxygen-glucose deprivation: involvement of glutamate uptake and reactive oxygen species
Canas PT, et al.
Anesthesiology, 105(5), 990-990 (2006)
Natalie J Hannan et al.
The Journal of clinical endocrinology and metabolism, 89(12), 6119-6129 (2004-12-08)
Leukocytes are critical mediators of endometrial remodeling, but the mechanisms by which leukocyte subpopulations enter the uterus are currently unknown. Endometrial leukocytes have no genomic progesterone receptors; thus, we hypothesized that leukocyte migration is induced indirectly by progesterone-regulated chemokines. Fractalkine

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