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B1156000

Bufexamac

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-(p-Butoxyphenyl)acetohydroxamic acid

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About This Item

Empirical Formula (Hill Notation):
C12H17NO3
CAS Number:
2438-72-4
Molecular Weight:
223.27
MDL number:
MFCD00078936
UNSPSC Code:
41116107
PubChem Substance ID:
329773173
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

bufexamac

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCOc1ccc(CC(=O)NO)cc1

InChI

1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)

InChI key

MXJWRABVEGLYDG-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bufexamac EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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P Koch et al.
Contact dermatitis, 31(2), 97-101 (1994-08-01)
4 patients developed an erythema-multiforme-like reaction following acute contact dermatitis from 2 different bufexamac-containing topical preparations. Histologically, the lesions did not show changes that were typical of erythema multiforme. Patch testing gave positive reactions to bufexamac at 1, 2, 3
A Bauer et al.
Deutsche medizinische Wochenschrift (1946), 124(40), 1168-1170 (1999-11-05)
A 49-year-old woman presented with acute perianal vesicular/bullous contact dermatitis. Other areas were over the trunk, face, neck and wrists. She reported occasional application of an ointment (Mastu S) to treat her hemorrhoids. Patch tests (basic series, anal block, own

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