MABC97

Anti-S1PR4/EDG6 Antibody, clone 16B9.1

clone 16B9.1, from mouse

• Synonym(s): Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 16B9.1, monoclonal
• species reactivity: rat, human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgMκ
• NCBI accession no.: NP_003766
• UniProt accession no.: O95977
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... S1PR4(8698)

Description

General description

Sphingosine 1-phosphate receptor 4 (S1PR4), otherwise known as EDG6, is present, in varying expression levels, in the adult lymph node, bone marrow, and thymus, as well as fetal liver, lung, and thymus. It is activated by the lysosphingolipid sphingosine 1-phosphate, and is coupled to Gi and G12/13 G proteins and via their various effector molecules, SIP4 regulates cell proliferation, differentiation, motility, and migration.

Immunogen

GST-tagged recombinant protein corresponding to human S1PR4/EDG6.

Application

Detect S1PR4/EDG6 using this Anti-S1PR4/EDG6 Antibody, clone 16B9.1 validated for use in Western Blotting & IHC.

Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected S1PR4/EDG6 in human red bone marrow and human tonsil tissues.

Quality

Evaluated by Western Blot Analysis in rat spleen tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate.

Target description

~42 kDa observed

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable