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Key Documents

8.21046

Sigma-Aldrich

Propionamide

for synthesis

Synonym(s):

Propionamide

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About This Item

Empirical Formula (Hill Notation):
C3H7NO
CAS Number:
Molecular Weight:
73.09
MDL number:
UNSPSC Code:
12352111
EC Index Number:
201-172-1
NACRES:
NA.22

Quality Level

form

crystals

mp

75-78 °C

storage temp.

2-30°C

InChI

1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

InChI key

QLNJFJADRCOGBJ-UHFFFAOYSA-N

Application


  • Reductive methylation under phase-transfer catalysis: Propionamide was employed in the reductive methylation of homogeneous primary beta-lauryl/myristyl polyethyleneoxy ethylamines under phase-transfer catalysis, illustrating its role in chemical synthesis and its potential as a chemical intermediate in various industrial processes (Jianu, 2021).

  • GPX4 degraders in medical chemistry: Research on the structure-activity relationship of RSL3-based GPX4 degraders incorporated propionamide, highlighting its application in pharmaceutical research, particularly in the development of novel therapeutic agents targeting oxidative stress pathways (Zheng et al., 2023).

Analysis Note

Assay (ex N): ≥ 98.0 %
Melting range (lower value): ≥ 78 °C
Melting range (upper value): ≤ 82 °C
Identity (IR): passes test

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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