208698-M

Calmodulin, Human Brain

Calmodulin, Human Brain, is a ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from human brain.

• Synonym(s): CaM, Ca ²⁺/Calmodulin, CaM, Ca²⁺/Calmodulin
• UNSPSC Code: 12352202

Properties

• Quality Level: 100
• Assay: ≥95% (native PAGE)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• storage temp.: −20°C

Description

General description

Calmodulin purifed from human brain.

Calmodulin purifed from human brain. Calmodulin is a ubiquitous Ca²⁺-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca²⁺-calmodulin complex is involved in the maintenance of intracellular Ca²⁺ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.

Physical form

Lyophilized from protein solution with 2 mM EDTA.

Reconstitution

Reconstitute with distilled water. H₂O (1 mg/ml)

Other Notes

O′Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci.15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable