03-0185-00
SMC® Human Total Tau High Sensitivity Immunoassay Kit
Synonym(s):
Microtubile-associated protein tau immunoassay kit, Neurofibrillary tangle protein immunoassay kit, Tau Single Molecule Counting Kit, Tau ultra-sensitive immunoassay
About This Item
Recommended Products
species reactivity
human
manufacturer/tradename
SMC®
assay range
sensitivity: 4.69 pg/mL
((lower limit of quantification))
inter-assay cv: ≤4%
intra-assay cv: ≤8%
(Intra-assay CV n=5; Inter-assay n=3)
Related Categories
General description
The SMC® Human Total Tau High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2) The Erenna and TM="SMCxPRO"] immunoassay systems detect analytes using Single Molecule Counting SMC® technology.
Specificity
- Non Human Primate – 50%
- Mouse – 100%
- Rat – 100%
- Canine – 100%
- Feline – 75%
Application
This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
Research Category:
Neuroscience
neurological
Research Sub-Category:
Alzheimer′s Disease
Aging, Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
Components
- Assay Buffer
- Total Tau Coated Beads
- Standard Diluent
- Total Tau Detection Antibody
- Total Tau Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
Specifications
Minimum of 4 plasma samples spiked with average recovery of 82% with a range of 76-88%
Minimum of 5 CSF samples spiked with average recovery of 91% with a range of 85-106%
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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Related Content
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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