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870520P

Avanti

18:1 CDP DG

Avanti Polar Lipids 870520P, powder

Synonym(s):

1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C48H91N5O15P2
CAS Number:
Molecular Weight:
1040.21
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (870520P-25mg)
pkg of 1 × 5 mg (870520P-5mg)

manufacturer/tradename

Avanti Polar Lipids 870520P

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C48H85N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56;;/h17-20,35-36,40-41,45-47,54-55H,3-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56);2*1H3/b19-17-,20-18-;;/t40-,41-,45+,46?,47-;;/m1../s1

InChI key

NECNTGAHQCHVGS-BQGZBBTBSA-N

Application

18:1 CDP DG (1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate)) may be used in preparation of liposomes.

Biochem/physiol Actions

18:1 CDP DG (1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate)) is a diacylglycerol derivate. It acts as a substrate for phosphatidylserine synthase (Pss), an enzyme involved in the synthesis of phospholipids in various organisms. CDP-diacylglycerol serves as a precursor for the biosynthesis of phosphatidylinositides. Dysregulated CDP-diacylglycerol signaling pathway leads to depression.

Packaging

5 mL Clear Glass Sealed Ampule (870520P-25mg)
5 mL Clear Glass Sealed Ampule (870520P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kimberly R Tyeryar et al.
BMC neuroscience, 9, 12-12 (2008-01-26)
Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple

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