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860597P

Avanti

C24:1 Lactosyl(β) Ceramide (d18:1/24:1)

Avanti Polar Lipids 860597P, powder

Synonym(s):

D-lactosyl-β1-1′-N-nervonoyl-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C54H101NO13
CAS Number:
483370-78-1
Molecular Weight:
972.38
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860597P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860597P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

General description

Lactosylceramide (LacCer) is a glycosphingolipid, which has a hydrophobic ceramide lipid and a hydrophilic sugar moiety. It is present mainly in the nervous system and myelin sheath.

Biochem/physiol Actions

Lactosylceramide (LacCer) is a structural and signaling lipid. It aids microbial attachment and also functions as an adhesion receptor for pathogens. LacCer is essential for signal transduction and cell adhesion. It controls cell proliferation and apoptosis. LacCer is implicated in cellular stress response and microbial pathogenesis. It facilitates innate immune responses and host-tissue pathogen interactions.

Packaging

5 mL Amber Glass Screw Cap Vial (860597P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in

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