850152P

18:1 PI(5)P

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate) (ammonium salt), powder

• Synonym(s): PIP[5′](18:1/18:1)
• Empirical Formula (Hill Notation): C₄₅H₉₀N₂O₁₆P₂
• CAS Number: 1246303-10-5
• Molecular Weight: 977.15
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850152P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850152P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850152P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

Description

General description

18:1 PI(11)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate)) is an ammonium salt of modified lipid. Approximately 0.5% of total phosphoinositides (PI) in mammalian cells consists of PI5P.

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

18:1 PI(11)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate) (ammonium salt)) has been used in protein−lipid overlay assay. It may be used in liposome preparation and in liposome preparation for liposome pull-down experiments.

Biochem/physiol Actions

Phosphatidylinositol 5-phosphate (PI5P) is known to control chromatin organization and gene expression. It can also act as a coordinator of actin cytoskeleton, membrane trafficking and signaling. It participates in autophagy.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850152P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850152P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids