810131P
Avanti
16:0-12:0 NBD PC
Avanti Polar Lipids 810131P, powder
Synonym(s):
1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphocholine
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C42H74N5O11P
CAS Number:
Molecular Weight:
856.04
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810131P-1mg)
pkg of 5 × 1 mg (810131P-5mg)
pkg of 5 × 2 mg (810131P-10mg)
manufacturer/tradename
Avanti Polar Lipids 810131P
lipid type
fluorescent lipids
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes and a prime metabolite of glycerolipid metabolism. It is present in the mucosal layer of the colon. In NBD PC, the fluorescent 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) label is linked to phosphatidylcholine.
Application
16:0-12:0 NBD PC may be used:
- in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes
- as a fluorophore for 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in fluorescence recovery experiments
- as a substrate to test scramblase activity
Biochem/physiol Actions
The use of 7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) as fluorescent probes in lipid membranes is involved in the study of various cellular processes.
Packaging
5 mL Amber Glass Screw Cap Vial (810131P-10mg)
5 mL Amber Glass Screw Cap Vial (810131P-1mg)
5 mL Amber Glass Screw Cap Vial (810131P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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C Scomparin et al.
The European physical journal. E, Soft matter, 28(2), 211-220 (2008-12-23)
The diffusion law of DMPC and DPPC in Supported Lipid Bilayers (SLB), on different substrates, has been investigated in details by Fluorescence Recovery After Patterned Photobleaching (FRAPP). Over micrometer length scales, we demonstrate the validity of a purely Brownian diffusive
Ellen C Wrobel et al.
Physical chemistry chemical physics : PCCP, 22(11), 6154-6166 (2020-03-04)
The antibacterial activity of a calixarene derivative, p-tert-butylcalix[6]arene (Calix6), was assessed and was shown not to inhibit the growth of E. coli, S. aureus and B. subtilis bacteria. With the aim of gaining more insights into the absence of antibacterial
R Derradi et al.
Langmuir : the ACS journal of surfaces and colloids, 35(47), 15232-15241 (2019-11-09)
Matrix vesicles (MVs) are a special class of extracellular vesicles that drive bone and dentin mineralization by providing the essential enzymes and ions for the nucleation and propagation of mineral crystals. Tissue-nonspecific alkaline phosphatase (TNAP) is an integral protein of
Rachel R Kroe et al.
Analytical biochemistry, 390(1), 1-13 (2008-12-24)
Analytical ultracentrifugation is a widely used method for characterizing the solution behavior of macromolecules. However, the two commonly used detectors, absorbance and interference, impose some fundamental restrictions on the concentrations and complexity of the solutions that can be analyzed. The
In vitro skin penetration enhancement techniques: A combined approach of ethosomes and microneedles.
C Bellefroid et al.
International journal of pharmaceutics, 572, 118793-118793 (2019-11-13)
Dermal administration of different macromolecules, such as nucleic acids, remains a real challenge because of the difficulty of crossing the main skin barrier, the stratum corneum (SC). To overcome this barrier, the use of deformable lipid-based nanovectors were developed to
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