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ALD00196

Sigma-Aldrich

2,4,6-Trichlorobenzenesulfonyl fluoride

95%

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About This Item

Empirical Formula (Hill Notation):
C6H2Cl3FO2S
Molecular Weight:
263.50
UNSPSC Code:
12352100
PubChem Substance ID:
329772630
NACRES:
NA.22

Quality Level

100

Assay

95%

form

liquid

reaction suitability

reaction type: click chemistry

refractive index

n20/D 1.568

density

1.655 g/mL at 25 °C

SMILES string

FS(C1=C(Cl)C=C(Cl)C=C1Cl)(=O)=O

InChI

1S/C6H2Cl3FO2S/c7-3-1-4(8)6(5(9)2-3)13(10,11)12/h1-2H

InChI key

YIYMNRBLYKOKQM-UHFFFAOYSA-N

Application

Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Certificates of Analysis (COA)

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Articles

SuFEx: Sulfonyl Fluorides that Participate in the Next Click Reaction

In collaboration with K. Barry Sharpless and coworkers, Sigma-Aldrich now offers a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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