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933597

Sigma-Aldrich

Poly(Guluronate)

low endotoxin

Synonym(s):

Alginate, Bioink, Bioprinting, Guluronic Acid, Hydrogel, Ionic, Sodium Alginate

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About This Item

Linear Formula:
(C6H8O6)n
UNSPSC Code:
12352201
NACRES:
NA.21
form:
(Solid chunks, fibres or powder)

description

GPC 5-15 kDa

Quality Level

100

form

(Solid chunks, fibres or powder)

impurities

<125 EU/g Endotoxin
<5 CFU/g Bioburden(Total aerobic)
<5 CFU/g Bioburden(fungal)

color

white to off-white

storage temp.

2-8°C

Related Categories

General description

Sodium alginate is a natural linear polysaccharide derived from brown algae made up of blocks of B-D-mannuronate (M) and a-L-guluronate (G). Guluronate blocks that bind Ca2+ cations to form ionic bonds. Poly(guluronate) is isolated from alginate which can be used alone as a stabilizer or further modified to create additional functional groups.

Application

Sodium Alginate based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug delivery applications.

Features and Benefits

  • Sterile, low endotoxin
  • Batch control offers reproducible models for preclinical toxicology testing and drug screening
  • Extended shelf-life & stability

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Kuen Yong Lee et al.
Biomaterials, 25(13), 2461-2466 (2004-01-31)
Hydrogels, chemically cross-linked or physically entangled, have found a number of applications as novel delivery vehicles of drugs and cells. However, the narrow ranges of degradation rates and mechanical strength currently available from many hydrogels limits their applications. We have

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