931845

GenOx-PJ

• Synonym(s): 3-Oxo-2-tosyl-2,3-dihydro-1H-1λ₃-benzo[d][1,2]iodazol-1-yl acetate
• Empirical Formula (Hill Notation): C₁₆H₁₄INO₅S
• CAS Number: 2243393-44-2
• Molecular Weight: 459.26
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• form: powder
• Quality Level: 100
• mp: >300 °C
• functional group: iodo
• storage temp.: −20°C

Description

Application

GenOx-PJ is an iodine(III) based oxidant developed by Genentech as part of a robust method of forming C-O bonds through direct coupling of carboxylic acids with alcohols. When used with a Ru(II) photocatalyst, GenOx-PJ is active in the decarboxylative coupling of a broad range of carboxylic acids--including primary, secondary, tertiary, as well as peptides--with alcohols. By this method, GenOx-PJ enables a direct approach in utilizing simple, readily available substrates to perform this type of coupling, and providing many synthetic applications.

Other Notes

A Platform for Decarboxylative Couplings via Photoredox Catalysis: Direct Access to Carbocations from Carboxylic Acids for Carbon−Oxygen Bond Formation

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable