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855286

Sigma-Aldrich

5-Aminouracil

98%

Synonym(s):

5-Amino-2,4-dihydroxypyrimidine, 5-Amino-2,4-pyrimidinediol

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About This Item

Empirical Formula (Hill Notation):
C4H5N3O2
CAS Number:
932-52-5
Molecular Weight:
127.10
Beilstein:
127250
EC Number:
213-252-3
MDL number:
MFCD00006025
UNSPSC Code:
12352100
PubChem Substance ID:
24888374
NACRES:
NA.22

Quality Level

200

Assay

98%

form

powder

mp

>300 °C (lit.)

SMILES string

NC1=CNC(=O)NC1=O

InChI

1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)

InChI key

BISHACNKZIBDFM-UHFFFAOYSA-N

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Paulina Spisz et al.
International journal of molecular sciences, 21(17) (2020-09-05)
Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that
A González-Fernández et al.
Mutation research, 106(2), 255-264 (1982-12-01)
Chromosome damage induced in root meristems of Allium cepa L. by an 18-h treatment with 5-aminouracil (AU) was enhanced by 2-h pulses with 5 mM caffeine, the most effective pulse being given from the 8th to the 10th h after
R Sen et al.
Cell biology international, 22(11-12), 867-874 (2000-06-30)
Onion root-tip cells were blocked at S-phase by treating them with 5-aminouracil (5AU). These cells were then further treated with caffeine/2-aminopurine (Caf/2AP) or a combination of both in the presence of 5AU. These tyrosine kinase inhibitors were able to induce
Del Campo et al.
Biology of the cell, 95(8), 521-526 (2003-11-25)
In the multinucleate cells induced in Allium cepa L. meristems, the nuclei surrounded by the largest cytoplasm environment complete replication earlier (advanced nuclei), but have a longer G2, than the others (delayed nuclei). Thus, all nuclei break down the nuclear
K K Upadhyay et al.
Organic & biomolecular chemistry, 8(21), 4892-4897 (2010-09-08)
A new fluorescent probe (5-[(4-diethylamino-2-hydroxy-benzylidene)-amino]-1H-pyrimidine-2, 4-dione) (Receptor 1) has been synthesized by the Schiff base condensation of 5-aminouracil with 4-(diethylamino)salicylaldehyde. The receptor 1 exhibits high selectively for Al(3+) in DMSO as well as in aqueous solution even in the presence
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