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Sigma-Aldrich

Trimethylamine-d9 N-Oxide

98 atom % D, 98% (CP)

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About This Item

Empirical Formula (Hill Notation):
C3D9NO
CAS Number:
Molecular Weight:
84.17
UNSPSC Code:
12352116
PubChem Substance ID:

isotopic purity

98 atom % D

Assay

98% (CP)

form

solid

technique(s)

bio NMR: suitable

mass shift

M+9

SMILES string

[O-][N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3

InChI key

UYPYRKYUKCHHIB-GQALSZNTSA-N

Related Categories

General description

Trimethylamine-d9 is isotopically enriched molecule.

Application

Trimethylamine-d9 N-oxide is used in the stability of hydrogen bonding between peptide, water with trimethylamine N-oxide.It is also used as an internal standard for the quantification of trimethylamine N-oxide by GC- or LC-MS.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Makiko Shimizu et al.
The Journal of toxicological sciences, 43(6), 387-393 (2018-06-08)
Medicinal carnitine-derived and dietary-derived malodorous trimethylamine and its non-malodorous metabolite trimethylamine N-oxide were historically regarded as nontoxic. Clinical and toxicological interest has recently arisen because of their potential association with atherosclerosis. We previously reported a human physiologically based pharmacokinetic (PBPK)
Tsung-Jen Lin et al.
Nutrition (Burbank, Los Angeles County, Calif.), 66, 29-37 (2019-06-16)
A plant-based diet has been associated with a reduced risk of cardiovascular (CV) diseases. This study aimed to determine the levels and correlations of CV-related biomarkers and the beneficial role of dietary habits. A total of 63 healthy vegetarians (n = 32)
W H Wilson Tang et al.
Circulation research, 116(3), 448-455 (2015-01-20)
Trimethylamine-N-oxide (TMAO), a gut microbial-dependent metabolite of dietary choline, phosphatidylcholine (lecithin), and l-carnitine, is elevated in chronic kidney diseases (CKD) and associated with coronary artery disease pathogenesis. To both investigate the clinical prognostic value of TMAO in subjects with versus

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