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Key Documents

670340

Sigma-Aldrich

Fmoc-pentafluoro-L-phenylalanine

≥97%

Synonym(s):

(S)-2-(Fmoc-amino)-3-(pentafluorophenyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):
C24H16F5NO4
CAS Number:
Molecular Weight:
477.38
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

Quality Level

Assay

≥97%

optical activity

[α]/D -20.5±1.0°, c = 1 in methanol

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)OCC2c3ccccc3-c4ccccc24

InChI

1S/C24H16F5NO4/c25-18-15(19(26)21(28)22(29)20(18)27)9-17(23(31)32)30-24(33)34-10-16-13-7-3-1-5-11(13)12-6-2-4-8-14(12)16/h1-8,16-17H,9-10H2,(H,30,33)(H,31,32)/t17-/m0/s1

InChI key

DLOGILOIJKBYKA-KRWDZBQOSA-N

Hazard Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Lee Schnaider et al.
ACS applied materials & interfaces, 11(24), 21334-21342 (2019-05-29)
The rapid advancement of peptide- and amino-acid-based nanotechnology offers new approaches for the development of biomedical materials. The utilization of fluorenylmethyloxycarbonyl (Fmoc)-decorated self-assembling building blocks for antibacterial and anti-inflammatory purposes represents promising advancements in this field. Here, we present the

Articles

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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