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Key Documents

26564

Sigma-Aldrich

Chlorotripyrrolidinophosphonium hexafluorophosphate

≥98.0% (AT)

Synonym(s):

PyCloP

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About This Item

Linear Formula:
C12H24ClN3P · PF6
CAS Number:
Molecular Weight:
421.73
Beilstein:
6842341
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98.0% (AT)

form

solid

reaction suitability

reaction type: Coupling Reactions

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.Cl[P+](N1CCCC1)(N2CCCC2)N3CCCC3

InChI

1S/C12H24ClN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1

InChI key

BSCYRXJVGSZNKX-UHFFFAOYSA-N

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Application

Reagent for:
Peptide coupling reactions and synthesis of coupling reagents
Sequence selective peptide recognition
Synthesis of condensing reagents
Synthesis of heterocyclic β-sheet ligands

Other Notes

Crystalline reagent for peptide coupling of N-alkylated N-Fmoc and N-Z amino acids in high yield and without racemization.

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J. Coste et al.
The Journal of Organic Chemistry, 59, 2437-2437 (1994)

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